Review of Amicus Therapeutics Biopharmaceutical Achievement

Founded in 2002, Amicus Therapeutics is a public biopharmaceutical company that handles devastating rare and orphan illnesses. The firm focuses on disorders collectively referred to as Lysosomal Storage Disorders (LSDs). They include Pompe disease, Fabry disease, CDKL5, and rare genetic connective skin disorders called Epidermolysis Bullosa (EB).

 

Based in Cranbury, New Jersey, Amicus Therapeutics goal involves making the lives of the patients meaningful. The company collaborates with patients, health practitioners, and the caregivers to assist the rare disease community. They have utilized the aspect of science to invent and develop effective Enzyme Replacement Therapies (ERT). The company’s product is founded in a big way on the Chaperone-Advanced Replacement Therapy (CHART).

 

Amicus Therapeutics Chairman and CEO, John F. Crowley has been involved with biotechnology stems since 1998 after losing his two children with Pompe disease. John Crowley has dedicated his life to developing remedies for Pompe disease as well as other rare disorders. He has enabled the company to develop a technology called pharmacological chaperone that treat specific LSDs. This LSDs have traits of unfolded, unstable or misfolded mutated proteins. The technology is designed with tiny molecules which selectively target enzyme with the aim of stabilizing and turning it into the required three-dimensional shape.

 

The company’s leading product, though in the last stage of development, is referred to as Migalastat (https://finance.yahoo.com/quote/FOLD?ltr=1). The personalized medicine is meant to treat patients with Fabry disorder on the ground of individual genetic diagnosis. For the Epidermolysis Bullosa, Amicus Therapeutics is developing a first to market therapy called SD-101. Its topping biological program is the ATB200/AT2221, a different Pompe disease ERT that will be combined with the pharmacological chaperone.

 

Amicus Therapeutics in its development has collaborated with other companies as well acquiring others. In 2010, it worked with JCR pharmaceutical and GlaxoSmithKline to research on alpha-galactosidase. In 2013, it acquired a competitor, Callidus Biopharma as well as Scioderm in 2015.

Why Osteo Relief Institute is a go-to Clinic for Managing Osteoarthritis

Even though arthritis is a common condition, it is often misunderstood. In fact, it is used as a general term for joint disease or pain as opposed to a single disease. With over 100 varying types of arthritis, osteoarthritis has proven to be the most common. This arthritis condition is characterized by the disintegration of cartilage, which is the soft tissue between the joints.

 

Some of the risk factors for osteoarthritis comprise of previous injury, family history, excess weight, and age. Being a degenerative and incurable disease means that patients ought to consider self-management in reducing the scope and speed of the condition’s impact.

 

About Osteo Relief Institute

 

The New Jersey-based Osteo Relief Institute is an independently held body that boasts a team of qualified staff as far as communication and patient care are concerned. In fact, the professionals have top-in-line art equipment, which provides an edge when it comes to offering pain relief solution that is long lasting to their patients. Since the institute’s technology is cleared for use and FDA approved, osteoarthritis patients cannot lack a solution to meet their needs.

 

Physical therapists and board-certified physicians at Osteo Relief Institute hold a firm belief that patients ought to be treated like family members (LinkedIn). For this reason, the number one objective for these experts involves helping patients avert surgery by providing effective and safe treatments. Each of the institute’s location is not only independently owned but also highly trained in patient-centered communication and care.

 

For treatment purposes, Osteo Relief Institute provides a groundbreaking combination of cleared and FDA approved treatments and techniques that are charted and tracked to evaluate relief and progress. The techniques used include videofluoroscopy, all-natural joint lubrication injections, advanced biomechanical bracing procedures, and non-grueling knee and spine strengthening. Additionally, each treatment plan is tailored to meet each patient’s needs.

 

The advanced techniques utilized by Osteo Relief Institute are useful in restoring normal biomechanics. They also help in strengthening lasting comfort and relief, maintaining healthy joint mobility, and providing natural knee and disc cushioning to promote the healing process. Furthermore, numerous leading insurance companies and Medicare cover most of Osteo Relief Institute’s treatments.

More at https://www.osteoreliefinstitute.com/relief-options/

Eli Gershkovitch And The Growth Of Steanworks Craft Beer Brewery

Many people consider Canadian craft beer to be among the best in the world. Micro-breweries all over the country produce a wide array of craft beer with unique flavors. And the number of Canadians that prefer craft beer to mass market beer has risen steadily for decades. These days, Canada is the home of a slew of award-winning craft beers and a growing number of international craft beer lovers are clamoring for Canadian craft beer. Many of the former Canadian micro-breweries that produce craft beer have now become macro-brewers with millions of fans of their products all over the world (About.me).

 

One example of the growth of the Canadian craft beer industry is Eli Gershkovitch and his Steamworks Brewery. Over the past 20 years, Eli Gershkovitch has grown Steamworks Brewery from a Canadian micro-brewery into an international craft beer empire with customers all over Canada, Europe, and the United States. And the former practicing attorney has seen his small brewpub grow to over 5 times its original size. He now owns a string of restaurants and bars where Steamworks craft beers are sold.

 

For Eli Gershkovitch Steamworks Brewery represents freedom. He gets to make the types of beer he lovers. He even bought out his former partner so he gets to decide how much and how fast his company grows. For Eli Gershkovitch that means growing slowly to meet the demands of his customers. But over the course of 20 years, his Steamworks Brewery has become an integral part of the local Vancouver culture that’s embraced by locals and tourists alike.

 

Eli Gershkovitch opened his Steamworks micro-brewery in Gastown, Vancouver in 1995. Initially, Steamworks Brewery only produced enough craft beer to supply his 184 seat beer pub. But as the pub grew to over 750 seats and more and more people throughout Canada and the United State began asking for his craft beers, he gradually expanded Steamworks Brewery and increased the types and amount of beer is produced. Today, Eli Gershkovitch is a craft beer industry veteran overseeing a burgeoning beer empire. And Eli Gershkovitch has the freedom he wanted.

More at https://ca.linkedin.com/company/steamworks-brewing-co.

A Look At Glen Wakeman’s Successful Career

Glen Wakeman is a business and finance expert. Over the years, he has been heavily involved in entrepreneurship, mentorship, and development of mergers and acquisitions. Glen is the founder and CEO of LaunchPad Holdings LLC, a SAAS company that he established in 2015. The company offers guidance to startup businesses. In an interview with Interview.net, Glen explained that he has witnessed many startups collapse due to lack of proper structures. He explained that many people have great ideas but fail to implement them owing to inadequate workable plans. To remedy this situation, Glen created a simple software platform, LaunchPad, to help entrepreneurs build their businesses easily. Before implementing an idea, the shrewd entrepreneur thinks through it and seeks the opinions of other people. As an entrepreneur, Glen capitalizes on innovation and customer satisfaction.

About Glen Wakeman

Glen Wakeman holds a BS degree in economics and finance from the University of Scranton. In addition, he earned his MBA from the University of Chicago. Glen started his career by working for GE Capital in P&L and business development. While at GE Capital, the firm’s board of directors recognized him as a role model for growth leadership. Later, he joined Doral Financial Corporation where he served as the CEO, president and chairman of the board. Glen founded and managed Nova Four. In the course of his career, Glen Wakeman has participated in the development of numerous businesses with some having as high as 17,000 staff members and $15 billion in assets.

While working with diverse businesses, Glen has concentrated on new market entry, exponential growth, and divestitures. He is reputable for his proven methodology of performance in five key areas, including leadership, risk management, governance, execution and human capital. With adequate experience in building businesses, Glen uses his writing skill to offer insightful counsel on different subjects like strategy, management and administration, emerging markets and international fiscal matters (PhillyPurge). The transformative leader mentors various C-level executives and offers advisory services to startups like Dreamfunded and Sitter Bees. Wakeman has lived in six countries where he has played a pivotal role in enhancing different businesses. Owing to his success, the executive has continued to receive significant international attention.

More about Glen Wakeman at https://www.dailyforexreport.com/glen-wakeman-business-leader-assisting-small-start-companies/

Dr. Mark Holterman: Helping Support Dreams

Dr. Mark Holterman is many things. He is a professor of pediatrics at the University of Illinois College of Medicine, as well as CEO of Mariam Global Health. He has maintained both positions for the past five years.

 

As a medical specialist, Dr. Mark Holterman is passionate about a few organizations at support causes in the medical field. One organization that Dr. Holterman supports is the International Pediatric Specialists Alliance for the Children of Vietnam (IPSAC-VN).

 

The International Pediatrics Specialists Alliance for the Children of Vietnam’s goal is to improve pediatric medical treatment for the children of Vietnam. The organization works to provide necessary supplies and other supplies to medical personnel.

 

The IPSAC-VN also supports their local resident’s dreams of working in the medical field by providing scholarships through its International Scholar Program (Doctors.HealthGrove). The program allows them to further their education at select institutions in the United States.

 

The scholars are provided with funding for traveling to the United States, and they get hosted to gain experience in medical research or in clinical examinations at a medical institution. After the program ends, the scholars speak to supporters of the International Scholar Program about using the knowledge they gained to help their local medical community in Vietnam.

 

Dr. Mark Holterman is a pediatric surgeon at the Advocate Christ Children’s Hospital, and The Children’s Hospital Illinois, St. Francis Medical Center. Dr. Holterman is also a member of the American College of Surgeons and the American Academy of Pediatrics, amongst other organizations. He specializes in pediatric surgery and conducts research on regenerative medicines, stem cell therapies, obesity, and novel cancer treatments.

 

Dr. Mark Holterman earned his degree in biology from Yale University and his MD and Ph.D. from the University of Virginia (http://www.vitals.com/doctors/Dr_Mark_Holterman.html). He then went on to complete his residency at the University of Virginia Health Sciences focusing on general surgery. Also, completed a fellowship at the Children’s Hospital and Medical Center through the University of Washington in pediatric surgery.

 

Stream Energy Empowers Its Consumers

Managing your power bills is a significant way of cutting down your total annual expenditure. Many consumers lose a significant amount of money every year to hidden energy costs. Have you ever received a surprising electricity bill for your home or office? Many would definitely say yes. Once in a while you get to be presented with a bill that is seriously higher than anticipated. It’s now possible to avoid this: thanks to Stream Energy’s usage control tools and tips.

 

 

It is important to understand that a great part of these hidden costs is contributed by household gadgets. Please note that Household electronics continue to consume power whenever they are plugged in. This is regardless of whether they are on standby or in use. The little energy they consume on a standby mode gradually amounts to a shocking power bill by end of the month. It is therefore recommended that you completely shut off all the electrical devices whenever they are not in use.

 

 

It is interesting to note that keeping your entertainment system shut when not in use can save you up to $130 annually. A similar response to a DVR saves about $36 and $1 to a coffee maker just to list a few. Remain in the light through weekly energy reports and avoid consumption surprises as result of a phantom drain.

 

 

Stream Energy

 

Stream Energy is a Dallas-based firm and a leading provider of various services in the global energy market. Established in 2005, Stream provides energy, protective, wireless, and home services across the United States.

 

 

From its Dallas headquarter, the company provides customized energy services in Illinois, Texas, Maryland, Georgia, and New Jersey just to mention a few. Through its multi-level marketing model, the company allows its associates to earn commissions from either selling products and services to consumers or bringing new associates on board.

 

 

Under the leadership of Rob Snyder and Pierre Koshajki as co-founders and Larry Mondry as president and CEO, Stream has generated over $8 billion in revenue since its inception (YouTube). It remains a leader among the direct selling companies in the business world. Currently, has about 500 employees, the company has been projected to continue its growth and expansion in the global market.

More about Stream Energy at https://www.saveonenergy.com/stream-energy/

Life Insurance 101: What To Know When Looking For Life Insurance

There is no doubt that life insurance is extremely important for nearly everyone to have. There are two different types of life insurance. Term life insurance is the first type of life insurance that may be available. Term life insurance is a good idea for those who need it to repay a debt or even for any of their children’s college education.

Term life insurance allows people to match the policy to the length of time you may need the life insurance. If you were buying a term life insurance policy for example for your child’s college education you would want to get something like a 20-year term life insurance policy. Learn more about Freedom Life Insurance: https://www.ehealthinsurance.com/ehealthinsurance/benefits/ifp/IHC-MultiState/IHC-MultiState-FreedomChoice-BR-0811.pdf and http://www.whitepages.com/business/freedom-life-insurance-co-of-america-fort-worth-tx

When it comes to this first life insurance policy choice it is only good for those who want life insurance for a certain period. If a term insurance policy is bought sometimes when the term is over it can be renewed but when renewing there will be a higher premium to renew it.

Permanent life insurance is for people who need insurance permanently. Permanent life insurance pays for a death benefit no matter how old you are when you die. Premiums for permanent life insurance is typically higher than term life insurance policy premiums are.

This is worth it in the end though because it remains the same with the permanent policy throughout your whole life and does not change like the term life insurance policy does when you renew it.

When looking for life insurance companies it is important to find one that is reputable. One of the most popular and reputable life insurance companies is Freedom Life insurance.

Freedom insurance is a company that provides people shopping for life insurance with some great options to choose from at affordable premium prices.

According to Crunchbase, Freedom Life insurance has great customer service to ensure that their customers are always happy and their policy premiums do not cost more than the average person can afford like other insurance companies do.

If you are shopping for life insurance be sure to check out Freedom life insurance before any other companies to get an idea of what you are looking for.

Securus Technologies Ensuring Law Enforcement Agencies Perform Better With The Use of Advanced Investigative Technologies

Inmate communication services are very necessary for the correctional facilities as it helps the people who are incarcerated to talk to their loved ones on a regular basis. There are a separate system and network that is different from the standard network, which is used to help the inmates and their families to communicate with each other. One of the companies that excel in providing such services is Securus Technologies. The company started its operations in the year of 1986 and since then has made massive contributions to the field through its innovative and cutting-edge technologies and services.

 

The CEO of Securus Technologies, Rick Smith, believes that inmate communication services are the right of the incarcerated people and also helps them relieve their stress caused due to isolation. In a way, it also helps in reducing the crime within the prison facilities. Securus Technologies currently provides its inmate communications and other associated services to over 3,000 prisons, and the count is increasing rapidly. It is because the company has been investing heavily in research and development to expand its service portfolio and reach out to further audience. In the past few years, Securus Technologies has spent close to $600 million for developing high-end inmate communications and crime prevention technologies and services. It would help in reducing the crime rate in the communities and empower the law enforcement agencies to perform better.

 

In a recent event, the company published a press release where it showcased a series of comments extracted from the letters and e-mails sent by the law enforcement officers. The letters spoke about how the company is helping in supporting their cause of reducing the crime rate in the society and keeping track of what the criminals are up to. The investigative technology offered by Securus Technologies is very advanced and is highly instrumental in crime prevention and evidence collection.

The Aspirations of Venture Capitalist and Philanthropist Marc Sparks

Marc Sparks is a successful venture capitalist and entrepreneur. Besides heading Timber Creek Capital, he also handles several portfolio businesses. Marc is renowned for his innate talent and expertise in growing companies. He is passionate about establishing businesses, bringing them to the top, and moving on to establish other businesses. Due to his business growth success, companies hire him to strengthen their presence in their industries and better their sales. Throughout his career, he has been broadly involved with a remarkable number of firms in the telecommunication industry. Some firms that have been associated with Marc Sparks include Splash Media, Blue Jay Wireless, and Cardinal Telecom.

 

Philanthropy Work

 

Besides business ventures, Marc Sparks has done extensive philanthropy work particularly in Dallas where he resides with his family. He is dedicated to providing what he can and giving back to the community to make Dallas area a better place. For many years, Sparks has been largely involved with the Samaritan Inn, a homeless shelter. He started working with the Samaritan Inn since the early 80s.

 

Marc Sparks has also been involved in other community work. For instance, he is in partnership with Habitat for Humanity, an organization committed to constructing small homes, particularly for homeless families. He also supports an organization known as American Can Academy. The organization is a magnet program designed specifically to help high schools in Dallas. Marc Sparks doesn’t just give donations. He volunteers his time too.

 

A couple of years ago, Marc developed a writing interest. He began writing a non-fiction book detailing his business journey and career so far. In his book titled “They Can’t Eat You,” Marc Sparks urges people not to give up. The book offers lots of important insights on how to handle a company and work in business. He highlights his rises and downfalls in business. However, he focuses more on the downfalls to inspire upcoming businessmen. Learn more: http://www.lulu.com/spotlight/marcsparks

 

Nathaniel Ru Believes Everything Should Last Longer

Sustainability is a huge part of the Sweetgreen lifestyle. Nathaniel Ru is the CEO of the company, and he knows he is doing everything he can to make the industry more sustainable. It is a part of the way he has made things better for those who are looking for a great bite to eat while they are also getting a convenient environment just like all of the other people who are in those situations.

Nathaniel Ru has always worked to make his company sustainable in a world where it can be difficult to get the freshest produce while still remaining sustainable.

Even when Nathaniel Ru was first starting Sweetgreen, he knew he was going to have to make some changes to the options he had for people. He has always tried his best to make the right decisions no matter what is going on. For Nathaniel Ru to do this, he had to be sure he would help people with all the issues they were dealing with.

Nathaniel Ru liked to give others the chance to make their lives better while they were eating food that was good for them. He wanted them to realize the food was sustainable as was the company. Learn more about Nathaniel Ru: http://fortune.com/2016/02/18/sweetgreen-entrepreneurs/

Since Nathaniel Ru knew what he was doing, he always tried his best to show people what would make the company better. He offered a lot of different options through Sweetgreen.

When people were able to choose these options, they would have a chance to make their own lives better. All of this is part of what Nathaniel Ru was intending when he first created Sweetgreen. It was a huge part of the way he was doing things no matter what was going on. For Nathaniel Ru to do this, he had to be sure people knew he was doing the best in the industry.

As Nathaniel Ru continued to help people with Sweetgreen, more people became interested in the industry. They knew they would have the chance to try different things while they were getting more from the options they had.

Nathaniel Ru has always relied on all the different opportunities he can create for others because of the way Sweetgreen has remained a great option for other people who are in the industry. Those who are looking for a safe, affordable and healthy alternative to their regular eating habits they have while they are in college.

Read more: Nathaniel Ru | Crunchbase and Nathaniel Ru | LinkedIn